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Use of SINEMET with dopamine-depleting agentse.greserpine and tetrabenazineor other drugs known to deplete monoamine stores is not recommended.

Abnormal uncontrolled movements including muscle twitching or spasmswhich may or may not resemble your Parkinson’s symptoms dizzinesslight-headedness when standing quickly feeling sicknauseavomitingloss of appetite discolouration of urinesweat and/or saliva dream abnormalities sleepiness or sudden onset of sleep slow movements twitching or spasm of the eyelids hair loss diarrhoea.

SINEMET is most helpful in improving slow movement and muscle stiffnessIt is also frequently helpful in treating shakingdifficulty in swallowing and drooling.

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